Dermotracin aerosol powder 150 ml
ديرموتراسين سبراي 150 مل
Bacitracin+neomycin
Unit price: 70.00 EGP
Specifications
Uses & Indications
Bacitracin and neomycin are topical antibiotics used for the prevention or treatment of minor skin infections caused by susceptible bacteria. This includes infections in minor cuts, scrapes, and burns. The combination provides broader antibacterial coverage.
How It Works
Bacitracin is a polypeptide antibiotic that inhibits bacterial cell wall synthesis by interfering with the dephosphorylation of the lipid carrier that transports peptidoglycan precursors across the bacterial cell membrane. It is primarily effective against Gram-positive bacteria. Neomycin is an aminoglycoside antibiotic that binds to the 30S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and leading to bacterial cell death. It is effective against a broad spectrum of Gram-negative bacteria and some Gram-positive bacteria.
Dosage & Administration
sachet
Adults: Apply a thin layer of powder to the affected area 1 to 3 times daily.
Children: Apply a thin layer of powder to the affected area 1 to 3 times daily. Consult a physician for use in infants.
topical
Adults: Apply a thin layer of ointment or cream to the affected area 1 to 3 times daily. The treated area may be covered with a sterile bandage.
Children: Apply a thin layer of ointment or cream to the affected area 1 to 3 times daily. Consult a physician for use in infants.
Side Effects
- Skin irritation (redness, itching, rash)
- Allergic contact dermatitis (occurs in 1-10% of patients, especially with neomycin)
Serious Side Effects
- Anaphylaxis (rare)
- Ototoxicity (hearing loss) or nephrotoxicity (kidney damage) if significant systemic absorption occurs (extremely rare with topical use on intact skin, but a risk with large areas of denuded skin or prolonged use)
- Superinfection with non-susceptible organisms
Contraindications
Hypersensitivity to bacitracin, neomycin, or any component of the formulation. Not for use in large areas of the body, deep or puncture wounds, serious burns, or animal bites without medical consultation. Not for ophthalmic use.
Drug Interactions
Systemic absorption is minimal with proper topical use, so significant drug interactions are unlikely. However, concurrent use with other nephrotoxic or ototoxic drugs (e.g., other aminoglycosides, furosemide) should be approached with caution if there is a risk of systemic absorption, such as with large areas of denuded skin.
Pregnancy & Lactation
Category: C
Animal reproduction studies have shown an adverse effect on the fetus, and there are no adequate and well-controlled studies in humans. However, potential benefits may warrant use of the drug in pregnant women despite potential risks. Systemic absorption is generally low with topical application. Consult your doctor or pharmacist before use during pregnancy.
Storage
Store at controlled room temperature, typically between 20°C to 25°C (68°F to 77°F). Protect from moisture and excessive heat. Keep out of reach of children.
Clinical Tips
Clean the affected area thoroughly before application. Do not use for more than 7 days unless directed by a healthcare professional. Discontinue use and consult a doctor or pharmacist if the condition worsens, symptoms persist for more than 7 days, or a rash or irritation develops. Avoid contact with eyes.
Frequently Asked Questions
What is bacitracin and neomycin used for?
This combination antibiotic is used to prevent or treat minor skin infections caused by certain bacteria in cuts, scrapes, and minor burns. It helps to stop the growth of bacteria on the skin.
How often should I apply bacitracin and neomycin?
Typically, it should be applied to the affected area 1 to 3 times daily. Always follow the specific instructions from your doctor or pharmacist regarding frequency and duration of use.
Can I use bacitracin and neomycin for deep wounds or serious burns?
No, this medication is generally not recommended for deep wounds, puncture wounds, serious burns, or animal bites. Consult a healthcare professional for such injuries as they may require different treatment.
What should I do if my skin gets irritated after using this medication?
If you experience increased redness, itching, rash, or any signs of worsening irritation, stop using the medication and consult your doctor or pharmacist. Allergic reactions, especially to neomycin, can occur.
Is it safe to use bacitracin and neomycin during pregnancy?
This medication is classified as Pregnancy Category C. While systemic absorption is generally low with topical use, it's important to consult your doctor to discuss the potential risks and benefits before using it during pregnancy.
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Medical Disclaimer
The information provided is for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor or pharmacist before starting or changing any medication.