Daflon 1000mg 30 f.c. tabs
دافلون 1000مجم 30 قرص
Diosmin+hesperidin
Unit price: 118.00 EGP
Specifications
Uses & Indications
Diosmin and hesperidin are flavonoid compounds primarily used for the treatment of chronic venous insufficiency (CVI) and its associated symptoms, such as heavy legs, pain, nocturnal cramps, and edema. They are also indicated for the symptomatic treatment of acute and chronic hemorrhoids.
How It Works
Diosmin and hesperidin work by improving venous tone and reducing venous distensibility, leading to a decrease in venous capacitance and stasis. They also reduce capillary permeability and enhance lymphatic drainage, which helps to alleviate edema. These actions are mediated through their effects on venous smooth muscle and microcirculation, including anti-inflammatory and antioxidant properties.
Dosage & Administration
tablet
Adults: For chronic venous insufficiency: Typically 1000 mg (containing 900 mg diosmin and 100 mg hesperidin) orally once daily. For acute hemorrhoidal attacks: 3000 mg daily (e.g., 1500 mg twice daily) for the first 4 days, followed by 2000 mg daily (e.g., 1000 mg twice daily) for the next 3 days. For chronic hemorrhoids: 1000 mg orally once daily.
Children: Not recommended for use in children. Consult a physician for alternative treatments.
Side Effects
- Gastrointestinal disturbances (e.g., nausea, dyspepsia, diarrhea, abdominal pain), occurring in approximately 2-5% of patients.
- Headache, reported in a small percentage of users.
Serious Side Effects
- Rare allergic reactions (e.g., rash, itching, urticaria).
- Severe abdominal pain or gastrointestinal bleeding (extremely rare, consult a doctor immediately if experienced).
Contraindications
This medication is contraindicated in individuals with known hypersensitivity to diosmin, hesperidin, or any of the excipients in the formulation.
Drug Interactions
Significant drug interactions with diosmin and hesperidin are generally considered rare. However, caution is advised when co-administered with anticoagulants (e.g., warfarin) due to a theoretical potential for increased bleeding risk, although clinical evidence is limited. Consult your doctor or pharmacist regarding all concomitant medications.
Pregnancy & Lactation
Category: B
Animal studies have not indicated direct or indirect harmful effects with respect to reproductive toxicity. Limited human data from clinical studies and post-marketing surveillance suggest no adverse effects on pregnancy or fetal/neonatal health. However, as a precautionary measure, use during pregnancy should only be considered if the potential benefit justifies the potential risk, and under the guidance of a healthcare professional.
Storage
Store the tablets below 30°C, protected from light and moisture. Keep out of reach of children.
Clinical Tips
To minimize potential gastrointestinal upset, it is often advised to take diosmin and hesperidin tablets with meals. For chronic venous insufficiency, consistent use over several months may be necessary to observe full therapeutic benefits. Lifestyle modifications such as regular exercise, elevating legs, and wearing compression stockings can complement the treatment.
Frequently Asked Questions
What is diosmin+hesperidin used for?
Diosmin and hesperidin are primarily used to treat symptoms of chronic venous insufficiency, such as heavy legs, pain, and swelling. They are also effective in managing acute and chronic hemorrhoids.
How should I take diosmin+hesperidin tablets?
For chronic venous insufficiency, take 1000 mg once daily. For acute hemorrhoids, the dosage is higher initially (3000 mg daily for 4 days) then reduced (2000 mg daily for 3 days). Always take it with meals to reduce stomach upset and follow your doctor's instructions.
What are the common side effects of diosmin+hesperidin?
Common side effects are generally mild and include gastrointestinal disturbances like nausea, diarrhea, dyspepsia, and abdominal pain. Headaches may also occur. These effects are usually transient.
Can I take diosmin+hesperidin during pregnancy?
While animal studies have shown no harm and limited human data are reassuring, it is classified as Pregnancy Category B. Consult your doctor before using this medication if you are pregnant or planning to become pregnant, to ensure it is safe for your specific situation.
How long does it take for diosmin+hesperidin to work?
For acute conditions like hemorrhoids, relief may be noticed within a few days. For chronic venous insufficiency, consistent use over several weeks to months is often required to experience the full therapeutic benefits and sustained symptom improvement.
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Medical Disclaimer
The information provided is for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor or pharmacist before starting or changing any medication.