Cardiovascular - Vascular Protective Agents

Diosmin plus 500 mg 30 f.c.tabs.

ديوزمين بلس 500مجم 30 قرص

Diosmin+hesperidin

111.00 EGP

Unit price: 37.00 EGP

Specifications

Manufacturer
Marcyrl co.
Units / Box
3
Barcode
6223003571870
Price Updated
Nov 20, 2024

Uses & Indications

Diosmin is primarily used for the treatment of symptoms related to chronic venous insufficiency (CVI), such as heavy legs, pain, restless legs, nocturnal cramps, and edema. It is also indicated for the treatment of hemorrhoids, including acute hemorrhoidal attacks and chronic hemorrhoidal disease.

How It Works

Diosmin acts as a venotonic and vasculoprotective agent. It prolongs the vasoconstrictor effect of norepinephrine on the venous wall, leading to increased venous tone and reduced venous distensibility and stasis. It also improves lymphatic drainage, decreases capillary permeability, and exhibits anti-inflammatory properties by inhibiting prostaglandin synthesis and leukocyte adhesion.

Dosage & Administration

tablet

Adults: For chronic venous insufficiency or chronic hemorrhoids: 500 mg twice daily (morning and evening) or 1000 mg once daily. For acute hemorrhoidal attacks: 1000 mg three times daily for 4 days, followed by 500 mg twice daily for 3 days.

Children: Not recommended. Consult a physician for specific guidance.

Side Effects

  • Gastrointestinal disturbances (e.g., nausea, vomiting, diarrhea, dyspepsia) (generally <2%)
  • Headache
  • Dizziness
  • Malaise

Serious Side Effects

  • Allergic reactions (e.g., rash, itching, urticaria)
  • Angioedema

Contraindications

Diosmin is contraindicated in individuals with known hypersensitivity to diosmin or any component of the formulation.

Drug Interactions

Limited significant drug interactions have been reported with diosmin. Theoretically, it may enhance the effects of anticoagulants or antiplatelet agents, though clinical significance is generally low. Caution is advised when co-administering with drugs metabolized by CYP enzymes, although diosmin's impact is considered minimal.

Pregnancy & Lactation

Category: Consult physician

Limited human data suggest no adverse effects when diosmin is used during pregnancy, particularly after the first trimester. However, it should only be used if clearly needed and under the direct supervision of a healthcare provider.

Storage

Store diosmin tablets at room temperature, typically between 20°C to 25°C (68°F to 77°F), away from moisture and direct heat. Keep the medication out of reach of children.

Clinical Tips

To minimize potential gastrointestinal upset, it is often recommended to take diosmin with meals. Consistent use is important for managing chronic conditions. For chronic venous insufficiency, lifestyle modifications such as regular exercise, elevating the legs, and wearing compression stockings are crucial alongside medication. For hemorrhoids, adequate fiber intake and hydration are essential.

Frequently Asked Questions

What is diosmin used for?

Diosmin is primarily used to treat symptoms of chronic venous insufficiency, such as heavy legs, pain, and swelling. It is also used for the treatment of hemorrhoids, both acute attacks and chronic conditions.

How should I take diosmin tablets?

For chronic conditions, diosmin is typically taken as 500 mg twice daily or 1000 mg once daily. For acute hemorrhoids, higher doses may be prescribed initially. It is often recommended to take it with meals to minimize gastrointestinal upset. Always follow your doctor's instructions.

What are the common side effects of diosmin?

Common side effects are usually mild and may include gastrointestinal disturbances like nausea, diarrhea, or indigestion, as well as headache or dizziness. These effects are generally transient.

Can I take diosmin if I am pregnant?

Limited human data suggest no adverse effects when diosmin is used during pregnancy, especially after the first trimester. However, it should only be used if clearly needed and under the direct supervision of your healthcare provider.

How long does it take for diosmin to work?

For chronic venous insufficiency, symptomatic improvement may be noticed within a few weeks, but consistent use over several months is often required for optimal benefits. For acute hemorrhoids, relief may be experienced within a few days.

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Medical Disclaimer

The information provided is for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor or pharmacist before starting or changing any medication.